Several project partners are in the process of developing databases for release of high-throughput data from the ZF-HEALTH project:

• The European Zebrafish Resource Center will establish a public database of available mutant stocks (WP1) which can be immediately requested through a link through the model organism database, ZFIN.

• All data from initial phenotpying of knock-out mutants (WP2) is made publicly available through the website of the Zebrafish Mutation Project. Transcript counting results will be made publicly available through a custom interface to be developed based on the experience of ArrayExpress.

• Standardised protocols for all assays (WP2) used to generate these results are being deposited in a public database in a format based on the EmPreSS database of mouse assays, and are accessible through the project website. It is currently implemented as a collection of PDFs.

• Iformation on enhancer elements, synteny blocks, and epigenetic marks (WP3) can be obtained for any region of the human genome through a custom genome browser, Ancora.
  
  
• All information from gene expression mapping of the brain (WP4) is released through our custom-designed online neuroanatomy atlas, ZebrafishBrain.org (developed in the ZF-MODELS project) and through other databases.

 

In order to avoid a duplication of programming effort, data will be released through existing external databases if suitable:

• Mutant data (WP1) will be released as sequence annotation through a track in the Ensembl browser.

• Addditionally, mutant data (WP1), initial phenotyping, behavioural phenotyping, and shelf screen results (WP2) as well as images of expression patterns of enhancer elements of human disease genes (WP4) will be submitted to ZFIN, the central model organism database for zebrafish.